INFORMATION CHANGE THE WORLD

International Journal of Information Engineering and Electronic Business(IJIEEB)

ISSN: 2074-9023 (Print), ISSN: 2074-9031 (Online)

Published By: MECS Press

IJIEEB Vol.3, No.2, Mar. 2011

Predicting Post-craniectomy ICP: A Comprehensive Compartmental Model including Decompressive Craniectomy

Full Text (PDF, 383KB), PP.49-55


Views:64   Downloads:1

Author(s)

Ketong Wang,Lie Li,Danqing Li,Yun Ding,Xiaoyang Zhou

Index Terms

Lumped-parameter model, decompressive craniectomy, intracranial pressure hydrodynamics, acute intracranial hypertension

Abstract

A novel lumped-parameter model is proposed to help with establish practice criteria of decompressive craniectomy and explain post-craniectomy intracranial dynamics. Besides traditional four major parts of arterial and venous blood, cerebrospinal fluid and brain tissue, another compartment produced by secondary intracranial hypertension is included here. The elliptical deflection solution under uniformly distributed pressure is introduced to compute the craniectomy compartment volume and incorporate it into existing differential equations. Under particular pathology in this paper our model predicts the waveform of post-craniectomy intracranial pressure, which measures the clinical effectiveness of such an operation. Then a statistical model—Gaussian fitting model is used to fit our simulation data. This quantitative model provides a possible way to designate the operation criteria such as the size of decompressive craniectomy. Finally we propose the optimal interval of craniectomy size as from 100 to 300 square centimeters and that larger than 400 square centimeters would not obviously reinforce pressure reduction anymore.

Cite This Paper

Ketong Wang,Lie Li,Danqing Li,Yun Ding,Xiaoyang Zhou,"Predicting Post-craniectomy ICP: A Comprehensive Compartmental Model including Decompressive Craniectomy", IJIEEB, vol.3, no.2, pp.49-55, 2011.

Reference

[1]A. Marmarou, A theoretical model and experimental evaluation of the cerebrospinal fluid system, Drexel University, Philadelphia, 1973.

[2]A. Marmarou, K. Shulman, R.M. Rosende, A nonlinear analysis of the cerebrospinal fluid system and intracranial pressure dynamics, J. Neurosurg., vol. 48 (3), pp. 332–344, 1978.

[3]O. Hoffmann, Biomathematics of intracranial CSF and haemodynamics. Simulation and analysis with the aid of a mathematical model, Acta Neurochir. Suppl., vol. 40, pp. 117–130, 1987.

[4]M. Ursino, A mathematical study of human intracranial hydrodynamics: part 1—the cerebrospinal fluid pulse pressure, Ann. Biomed. Eng., vol. 16 (4) , pp. 379–401, 1988.

[5]M. Ursino, A mathematical study of human intracranial hydrodynamics: part 2—simulation of clinical tests, Ann. Biomed. Eng., vol. 16 (4), pp, 403–416, 1988.

[6]H.L. Rekate, et al., Ventricular volume regulation: a mathematical model and computer simulation, Pediatr. Neurosci.v vol. 14 (2), pp. 77–84, 1988.

[7]C.A. Lodi, et al., Modeling cerebral autoregulation and CO2 reactivity in patients with severe head injury, Am. J. Physiol., vol. 274 (5 Pt. 2), pp. H1729–H1741, 1998.

[8]M. Czosnyka, et al., The hyperaemic response to a transient reduction in cerebral perfusion pressure. A modelling study, Acta Neurochir., vol. 115 (3–4), pp. 90–97, 1992.

[9]Z.M. Kadas, et al., A mathematical model of the intracranial system including autoregulation, Neurol. Res., vol. 19 (4), pp. (1997) 441–450.

[10]Delgado-Lopez P, Mateo-Sierra O, Garcia-Leal R, Agustin-Gutierrez F, Fernandez-Carballal C, Carrillo-Yague R. Decompressive craniectomy in malignant infarction of the middle cerebral artery. Neurocirugia (Astur); vol. 15, pp. 43–55, 2004.

[11]J. Albanese, M. Leone, J.R. Alliez, et al. Decompressive craniectomy for severe traumatic brain injury: Evaluation of the effects at one year. Crit Care Med, vol. 31, pp. 2535–2538, 2003;.

[12]Bergel, D.H. The static elastic properties of the arterial wall. J. Physiol., vol. 156, pp. 458-469, 1961.

[13]K. Hayashi, H. Handa, S. Nagasawa, A.Okumura, K. Moritake. Stiffness and elastic behaviorof human intracranial and extracranial arteries. J. Biomech., vol. 13, pp. 175-184, 1980.

[14]Y. Cai; Y.F. Liu; Y.P. Jiang; G.Q. Wu; S.X. Xu. The Simulation of Intracranial Pressure Dynamics. Shanghai J Biomed. Eng., vol. 26(2), pp. 67–70, 2005.

[15]Chien, W. Z; Large deflection of a circular clamped plate under uniform pressure; Chin. Jour. of Phys., vol. 7, pp. 102—114(1947).