The entire networking society is tremendously moving towards the IPv6 addressing architecture leaving behind the IPv4 address space. This happens due to the tremendous growth of Internet usage over the networking. The government has mandated that all the devices would be IPv6 compatible as the delay in the deployment of IPv6 would result in the negative impact of future growth and global connectivity of the internet. In this paper we are dealing with the impact of different interfaces like IPv4 only, IPv6 only and Dual stack mechanism over wireless networks with varying PHY and MAC layer interface of 802.11 a/g and 802.11 b standards. The results are simulated over Qualnet 5.1 simulator with various parameters like throughput, delay, jitter and packet delivery ratio is been calculated.