Jiri Skvor

Work place: Jan Evangelista Purkyně University in Ustí nad Labem, Ustí nad Labem, Czech Republic

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Research Interests: Computational Engineering, Computational Mathematics, Data Structures and Algorithms

Biography

Jiří Škvor is an assistant professor in the Department of Informatics at Faculty of Science, Jan Evangelista Purkyně University in Ústí nad Labem, Czech Republic. He obtained his PhD in computer methods in science and technology at the same faculty in 2009. His main research interests are in molecular simulations, computational geometry and percolation theory.

Author Articles
Technology of Gene Expression Profiles Filtering Based on Wavelet Analysis

By Sergii Babichev Jiri Skvor Jiri Fiser Volodymyr Lytvynenko

DOI: https://doi.org/10.5815/ijisa.2018.04.01, Pub. Date: 8 Apr. 2018

The paper presents the technology of gene expression profiles filtering based on the wavelet analysis methods. A structural block-chart of the wavelet-filtering process, which involves concurrent calculation of Shannon entropy for both the filtered data and allocated noise component is proposed. Simulation of the wavelet-filtering process was performed with the use of orthogonal and biorthogonal wavelets on different levels of wavelet decomposition and with the use of various values of the thresholding coefficient. Result of the simulation has allowed us to propose the technology to determine the optimal parameters of the wavelet filter based on complex analysis of the filtered data and allocated noise component.

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