Tyre building production line gradually transits from stand-alone production to combined production mode. The transformation of work mode from traditional serial intermittent to the parallel continuous has been the key technology research of tire production enterprise. And intelligent robots and other automated equipment have been the first choice of the tyre enterprise’s production line. Considering the combination of the equipment between upper and lower processes in tyre production line, the manual operations in some processes replaced by intelligent robots will improve production efficiency of tyre production enterprise, and will make outstanding contribution in reduce process losses and reduce production costs. This article studies on the key technology of combined application in production line, and makes simulation comparison for the same technical process that using different scheme, to prove the priorities and superiorities of combined production line relatives to the traditional production mode.