Disruption era had affected to every sector, including higher education sector. Between 2015 and 2019, more than 130 private university were closed for a different of reasons. Basically, they are not ready to face the change. Innovation disruption created new situations, thus created new demand while destroying prior situations. Many businesses collapsed suddenly because they are not aware of the inflection point that suddenly destroys the business model that has been run for years. Nevertheless, the current situation gave hints to new thoughts, including the development business model called infinite game theory. This paper examined how strategic inflection points can have occurred in the higher education sector and the infinite games model can be an alternative strategy in order the higher education sector withstand disruptive innovation era.