M. Pallikonda Rajasekaran

Work place: School of Electronics, Electrical and Biomedical Technology, Kalasalingam Academy of Research and Education, TamilNadu, India

E-mail: m.p.raja@klu.ac.in

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Research Interests:

Biography

Dr. M. Pallikonda Rajasekaran, graduated in Electronics and Instrumentation Engineering in 2001 from Shanmugha College of Engineering, Thanjavur and completed his M.Tech. degree in 2002 with second Rank in SASTRA University. He pursued his doctoral programme in Anna University, Chennai. He is currently working as professor in Kalasalingam Academy of Research and Education since 2012. He had a deep involvement in Bio-signal Processing research. Over 150 B.Tech students, 75 M.Tech students, and 8 Doctorates stand testimony for his productivity in Image Processing, Wireless Sensor Networks, and Biomedical Instrumentation research. He has published more than 50 papers in national and international journals and conferences. He is a life member of IETE.

Author Articles
Metaheuristic-enhanced Deep Learning Model for Accurate Alzheimer's Disease Diagnosis from MRI Imaging

By Nisha A.V. M. Pallikonda Rajasekaran R. Kottaimalai G. Vishnuvarthanan T. Arunprasath V. Muneeswaran R. Krishna Priya

DOI: https://doi.org/10.5815/ijisa.2025.01.05, Pub. Date: 8 Feb. 2025

Alzheimer’s Disease (AD) is the neuro-degenerative dementia, where the precise and early recognition of AD is vital for timely treatment to reduce mortality rate. A new automated model is implemented in this work for early discovery of AD in the Magnetic Resonance Imaging (MRI) brain scans. Initially, the input brain scans are taken from the Alzheimer's disease Neuroimaging Initiative (ADNI) database. Further, the acquired raw brain scans are visually improved by employing the binary normalization technique. The denoised brain scans are fed to the pre-trained Convolutional Neural Network (CNN) named GoogleNet for feature extraction. Next, the extracted richer feature values are fed to the Long Short Term Memory (LSTM) network for classifying the brain scan as Normal Control (NC), Mild Cognitive Impairment (MCI) and AD. In this manuscript, a Honey Badger Optimization Algorithm (HBOA) technique is incorporated with the LSTM networks for hyper-parameters optimization, where this procedure helps in diminishing the LSTM network’s complexity and computational time. The experimental results conducted on the ADNI database underscore the HBOA-based LSTM network's effectiveness, showcasing a remarkable mean classification accuracy of 97.83% in multi-class classification. Moreover, the sensitivity of HBOA based LSTM for AD/NC is 96.73% which is high when compared to the existing methodologies such as SVM with radial basis kernel function and NCSINs. This performance surpasses that of other comparative models for AD detection, emphasizing the superior capabilities and potential of the proposed method in the early detection.

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