Different from the traditional sense of self-study, this paper takes a new understanding of the definition and concept of autonomic learning. It brings forward the self-study mode called “target, design, implementation, and test”, and it raises the idea of establishing the platform of multimedia assistive autonomic learning so as to help the learners to fulfill a more efficient and motivating learning process. The case research is based on the intramural educating and learning website, and the evaluation is based on a comprehensive scoring system.